Bills sit No. 1 with a clean Week 2 showing, followed by Eagles, Ravens, Packers, and Chargers as Week 3 favorites. The rest of the league shifts with the Dolphins and Panthers sliding after rough outings, while Colts climb into the middle of the pack on explosive offense and emerging pieces. Bryce Young flashed in Carolina, Spencer Rattler impressed in New Orleans, and J.J. McCarthy looks like a work-in-progress in Minnesota as teams settle into schemes and fantasy roles.

Jauan Jennings played Week 2 through an ankle and shoulder issue, catching 5 of 10 targets for 89 yards and a touchdown while logging 87% of snaps. With George Kittle sidelined or limited, Week 3 vs Arizona could push Jennings for meaningful volume, provided the ankle remains minor. He’s listed day-to-day but is expected to play, offering upside as a high-variance flex option.

Key risk is the ankle flare; if Jennings suits up, he’s a volatile but potentially rewards-heavy play in deep leagues. Monitor Sunday updates and consider Jennings as a boom-or-bust flex with the upside to exploit a Cardinals defense that has shown vulnerability to pass-heavy schemes.

Week 3 brings sharp NFL line moves around key numbers 3, 7, 6, 14 and 10, with Bills-Dolphins surging to Bills -12.5 and Vikings-Bengals shifting on Burrow’s status and a McCarthy setback. Packers-Browns climbed as Green Bay’s defense dominates early, while a cluster of 42-45 point totals and six road favorites shape the slate. Injury news drives much of the movement, with Purdy, Burrow, Fields, Jayden Daniels and J.J. McCarthy in the spotlight and Ekeler/Jones shaping backfield expectations for fantasy and props.

The piece emphasizes how one quarterback can swing a spread, while OL/DL/WR injuries carry outsized impact when multiple starters are out. It also flags top receiving and backfield targets (Kittle, Goedert, Reed, Godwin, Darrisaw) as potential swing factors for props and DFS, and notes the evolving landscape of team totals and betting angles as Week 3 approaches.